SHENZHEN, CHINA and ROCKVILLE, MD, July 11, 2019 — HighTide Therapeutics Inc. (“HighTide”), a clinical-stage biopharmaceutical company, today announced that it has become a resident company at JLABS @ Shanghai.
“We are honored to be a resident at JLABS @ Shanghai,” said Liping Liu, Ph.D., Founder, CEO & CSO of HighTide. “Joining such a community is consistent with our mission to innovate and aim to develop novel therapies with global impact.”
Johnson & Johnson Innovation – JLABS (JLABS) is a network of open innovation ecosystems, enabling and empowering innovators across a broad healthcare spectrum including pharmaceutical, medical device, consumer and health tech sectors to create and accelerate the delivery of life-saving, life-enhancing health and wellness solutions to patients around the world. JLABS @ Shanghai is the first JLABS site in Asia-Pacific and the largest in the global JLABS network. The 4,400 square-meter incubator is located in Shanghai’s Zhangjiang Hi-Tech Park and follows the JLABS no-strings attached model, which means entrepreneurs are free to develop their science while holding onto their intellectual property.
About HighTide Therapeutics
HighTide Therapeutics Inc., founded in 2011 in Shenzhen, China, is dedicated to the discovery and development of innovative therapeutics for people suffering from gastrointestinal diseases and metabolic disorders with large and unsatisfied market needs. For additional information, please visit https://hightidetx.com/.
HTD1801, HighTide’s lead program, is a new molecular entity being developed for the treatment of NASH and PSC. HTD1801 has received U.S. Food and Drug Administration Fast Track designation for both NASH and PSC, and FDA Orphan Drug designation for PSC. HTD1801 is currently in Phase 2 proof of concept trials for NASH and PSC in the U.S.
Nonalcoholic steatohepatitis (NASH), a form of nonalcoholic fatty liver disease (NAFLD), is a chronic, complex liver disease characterized by hepatitis – inflammation of the liver – and liver cell damage, which can lead to fibrosis of the liver. NASH can lead to cirrhosis and liver cancer. Prevalence of NASH is on the rise and it may soon surpass hepatitis C as a cause for liver transplant. Currently, there are no approved therapies for NASH.
Primary sclerosing cholangitis (PSC) is a chronic, progressive liver disease characterized by inflammation and fibrosis of the bile ducts, leading to the formation of multifocal bile duct strictures. This cholestatic disease deteriorates to fibrosis, cirrhosis and ultimately liver failure, with an increased risk of malignancy. Currently, there are no approved therapies for PSC.